"The data add to recent signs from business surveys that growing uncertainty about the economic outlook is causing increasing numbers of firms to retrench and focus on cost cutting," said Chris Williamson, economist at economic research firm Markit.
The FTSE 100 Index turned lower 1.11 per cent to 5,722.01. The broader FTSE All-Share Index fell 1.04 per cent to 2,989.03.