On Wednesday's European afternoon trade, the Greenback was mixed versus its major counterparts, as traders eyed the upcoming ECB's policy meeting. The U.S. Dollar was modestly lower versus the Euro, losing 0.16%, with EUR/USD at 1.2586. The U.S. currency was also lower against the British Pound, with GBP/USD at 1.5916, which was a 0.29% increase. The Greenback gained 0.15% versus the Canadian Dollar, being traded at 0.9873.